Lysann Schläfke was born in 1987 in Plauen. She gained her first stage experience by the age of nine in the Theater Children's Choir and the Theaterfabrik Gera. After training as a diet and nutrition therapist, she completed her acting studies in 2013 at the Rostock Academy of Music and Theater. During her studies she played at the Junge Staatsschauspiel Braunschweig and at the Volkstheater Rostock. Her first engagement took her to the Schauspielhaus Chemnitz. Since 2017 Lysann Schläfke works freelance.
She performs at various theaters such as the new stage Senftenberg and Landesbühne Nord Wilhelmshaven. Beside that she works with young people, as an audiobook author and speaker and organizes cultural events.